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An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

Interleukin-6 (IL-6) is an important modulator of inflammation and immunity whose dysregulation is associated with a number of disease states. There is evidence of significant heritability in inter-individual variation in IL6 gene expression but the genetic variants responsible for this remain to be...

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Detalhes bibliográficos
Main Authors: Fairfax, Benjamin P., Vannberg, Fredrik O., Radhakrishnan, Jayachandran, Hakonarson, Hakon, Keating, Brendan J., Hill, Adrian V.S., Knight, Julian C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807371/
https://ncbi.nlm.nih.gov/pubmed/19942621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp530
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