Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting over two million patients in the US alone. Despite decades of research, surprisingly little is known regarding the molecular pathways underlying the pathogenesis of AF. ANK2 encodes ankyrin-B, a multifunctional ada...

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Detalhes bibliográficos
Main Authors: Cunha, Shane R., Hund, Thomas J., Hashemi, Seyed, Voigt, Niels, Li, Na, Wright, Patrick, Koval, Olha, Li, Jingdong, Gudmundsson, Hjalti, Gumina, Richard J., Karck, Matthias, Schott, Jean-Jacques, Probst, Vincent, Le Marec, Herve, Anderson, Mark E., Dobrev, Dobromir, Wehrens, Xander HT, Mohler, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211046/
https://ncbi.nlm.nih.gov/pubmed/21859974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.023986
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