Paired opposing leukocyte receptors recognizing rapidly evolving ligands are subject to homogenization of their ligand binding domains

Some leukocyte receptors come in groups of two or more where the partners share ligand(s) but transmit opposite signals. Some of the ligands, such as MHC class I, are fast evolving, raising the problem of how paired opposing receptors manage to change in step with respect to ligand binding propertie...

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Hlavní autoři: Fossum, Sigbjørn, Saether, Per Christian, Vaage, John Torgils, Daws, Michael Rory, Dissen, Erik
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210942/
https://ncbi.nlm.nih.gov/pubmed/21720914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0553-5
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