Paired opposing leukocyte receptors recognizing rapidly evolving ligands are subject to homogenization of their ligand binding domains

Some leukocyte receptors come in groups of two or more where the partners share ligand(s) but transmit opposite signals. Some of the ligands, such as MHC class I, are fast evolving, raising the problem of how paired opposing receptors manage to change in step with respect to ligand binding propertie...

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Главные авторы: Fossum, Sigbjørn, Saether, Per Christian, Vaage, John Torgils, Daws, Michael Rory, Dissen, Erik
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2011
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210942/
https://ncbi.nlm.nih.gov/pubmed/21720914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0553-5
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