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Paired opposing leukocyte receptors recognizing rapidly evolving ligands are subject to homogenization of their ligand binding domains

Some leukocyte receptors come in groups of two or more where the partners share ligand(s) but transmit opposite signals. Some of the ligands, such as MHC class I, are fast evolving, raising the problem of how paired opposing receptors manage to change in step with respect to ligand binding propertie...

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Main Authors: Fossum, Sigbjørn, Saether, Per Christian, Vaage, John Torgils, Daws, Michael Rory, Dissen, Erik
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210942/
https://ncbi.nlm.nih.gov/pubmed/21720914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0553-5
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