KLRE/I1 and KLRE/I2: A Novel Pair of Heterodimeric Receptors That Inversely Regulate NK Cell Cytotoxicity

NK cells identify infected, neoplastic, or MHC-disparate target cells via several different receptors. The NK cell receptor KLRE1 lacks known signaling motifs but has nevertheless been shown to regulate NK cell-mediated cytotoxicity. Here we demonstrate that KLRE1 forms functional heterodimers with...

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Main Authors: Saether, Per C., Westgaard, Ingunn H., Hoelsbrekken, Sigurd E., Benjamin, Jonathan, Lanier, Lewis L., Fossum, Sigbjørn, Dissen, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577148/
https://ncbi.nlm.nih.gov/pubmed/18713988
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