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Characterization of transglutaminase type II role in dendritic cell differentiation and function

DCs play an essential role in the endotoxic shock, and their profound depletion occurs in septic patients and septic mice. TG2(−/−) mice are more resistant to the endotoxic shock induced by LPS. Here, we studied the cellular and molecular basis of this effect, analyzing the role of the enzyme in DC...

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主要な著者: Matic, Ivana, Sacchi, Alessandra, Rinaldi, Alessandra, Melino, Gennaro, Khosla, Chaitan, Falasca, Laura, Piacentini, Mauro
フォーマット: Artigo
言語:Inglês
出版事項: The Society for Leukocyte Biology 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210574/
https://ncbi.nlm.nih.gov/pubmed/20371597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1009691
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