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Characterization of transglutaminase type II role in dendritic cell differentiation and function

DCs play an essential role in the endotoxic shock, and their profound depletion occurs in septic patients and septic mice. TG2(−/−) mice are more resistant to the endotoxic shock induced by LPS. Here, we studied the cellular and molecular basis of this effect, analyzing the role of the enzyme in DC...

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Autors principals: Matic, Ivana, Sacchi, Alessandra, Rinaldi, Alessandra, Melino, Gennaro, Khosla, Chaitan, Falasca, Laura, Piacentini, Mauro
Format: Artigo
Idioma:Inglês
Publicat: The Society for Leukocyte Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210574/
https://ncbi.nlm.nih.gov/pubmed/20371597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1009691
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