Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

The glucocorticoid receptor (GR), like other eukaryotic transcription factors, regulates gene expression by interacting with chromatinized DNA response elements. Photobleaching experiments in living cells indicate that receptors transiently interact with DNA on the time scale of seconds and predict...

Full description

Saved in:
Bibliographic Details
Main Authors: Voss, Ty C., Schiltz, R. Louis, Sung, Myong-Hee, Yen, Paul M., Stamatoyannopoulos, John A., Biddie, Simon C., Johnson, Thomas A., Miranda, Tina B., John, Sam, Hager, Gordon L.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210475/
https://ncbi.nlm.nih.gov/pubmed/21835447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.006
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items