Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism

The glucocorticoid receptor (GR), like other eukaryotic transcription factors, regulates gene expression by interacting with chromatinized DNA response elements. Photobleaching experiments in living cells indicate that receptors transiently interact with DNA on the time scale of seconds and predict...

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Detalhes bibliográficos
Main Authors: Voss, Ty C., Schiltz, R. Louis, Sung, Myong-Hee, Yen, Paul M., Stamatoyannopoulos, John A., Biddie, Simon C., Johnson, Thomas A., Miranda, Tina B., John, Sam, Hager, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210475/
https://ncbi.nlm.nih.gov/pubmed/21835447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.006
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