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Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity
Gene regulation often appears deterministic in the average cell population, but transcription is a probabilistic process at the single-cell level. Although many mechanisms are invoked to account for this behavior, it is difficult to determine how cell-to-cell variation in the interactions of transcr...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724732/ https://ncbi.nlm.nih.gov/pubmed/19126674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.035865 |
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