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Drosha processing controls the specificity and efficiency of global microRNA expression

microRNAs (miRNAs) are a large family of approximately 22-nucleotide-long RNAs that regulate gene expression. They are first transcribed as long, primary transcripts, which then undergo a series of processing steps to generate the single-stranded, mature miRNAs. Here, we showed that Drosha cleaved h...

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Detalhes bibliográficos
Main Authors: Feng, Yong, Zhang, Xiaoxiao, Song, Qingfeng, Li, Tongbin, Zeng, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210421/
https://ncbi.nlm.nih.gov/pubmed/21683814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2011.05.015
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