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Limiting CDRH-3 diversity abrogates the antibody response to the bacterial polysaccharide α 1→3 Dextran
Anti-polysaccharide antibody responses in mice are often oligoclonal, and the mechanisms involved in Ag-specific clone production and selection remain poorly understood. We evaluated the relative contribution of D(H) germline content versus N nucleotide addition in a classic oligoclonal, T-independe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210069/ https://ncbi.nlm.nih.gov/pubmed/21677133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100957 |
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