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Interleukin-7 enables antibody responses to bacterial polysaccharides by promoting B cell antigen receptor diversity

Polysaccharide vaccines such as the Vi polysaccharide of Salmonella enterica serovar Typhi induce efficient antibody responses in adults, but not in young children. The reasons for this difference are not understood. Interleukin-7 (IL-7) dependency in B cell development increases progressively with...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Dickinson, Gregory S., Levenson, Eric A., Walker, Justin A., Kearney, John F., Alugupalli, Kishore R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085875/
https://ncbi.nlm.nih.gov/pubmed/30006375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800162
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