Nucleophosmin deposition during mRNA 3′ end processing influences poly(A) tail length

During polyadenylation, the multi-functional protein nucleophosmin (NPM1) is deposited onto all cellular mRNAs analysed to date. Premature termination of poly(A) tail synthesis in the presence of cordycepin abrogates deposition of the protein onto the mRNA, indicating natural termination of poly(A)...

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Detaylı Bibliyografya
Asıl Yazarlar: Sagawa, Fumihiko, Ibrahim, Hend, Morrison, Angela L, Wilusz, Carol J, Wilusz, Jeffrey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209774/
https://ncbi.nlm.nih.gov/pubmed/21822216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.272
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