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Nucleophosmin deposition during mRNA 3′ end processing influences poly(A) tail length

During polyadenylation, the multi-functional protein nucleophosmin (NPM1) is deposited onto all cellular mRNAs analysed to date. Premature termination of poly(A) tail synthesis in the presence of cordycepin abrogates deposition of the protein onto the mRNA, indicating natural termination of poly(A)...

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Bibliografiset tiedot
Päätekijät: Sagawa, Fumihiko, Ibrahim, Hend, Morrison, Angela L, Wilusz, Carol J, Wilusz, Jeffrey
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2011
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209774/
https://ncbi.nlm.nih.gov/pubmed/21822216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.272
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