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Assays for determining poly(A) tail length and the polarity of mRNA decay in mammalian cells

This chapter describes several methods for measuring the length of the mRNA poly(A) tail and a novel method for measuring mRNA decay. Three methods for measuring the length of a poly(A) tail are presented: the poly(A) length assay, the ligation-mediated poly(A) test (LM-PAT) and the RNase H assay. T...

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Bibliografske podrobnosti
Main Authors: Murray, Elizabeth L., Schoenberg, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734468/
https://ncbi.nlm.nih.gov/pubmed/19111191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)02624-4
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