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The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

Craniofacial and skeletal dysmorphologies account for the majority of birth defects. A number of the disease phenotypes have been attributed to abnormal synthesis, maintenance and composition of extracellular matrix (ECM), yet the molecular and cellular mechanisms causing these ECM defects remain po...

詳細記述

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書誌詳細
主要な著者: Melville, David B., Montero-Balaguer, Mercedes, Levic, Daniel S., Bradley, Kevin, Smith, Jeffrey R., Hatzopoulos, Antonis K., Knapik, Ela W.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Limited 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209646/
https://ncbi.nlm.nih.gov/pubmed/21729877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007625
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