The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

Craniofacial and skeletal dysmorphologies account for the majority of birth defects. A number of the disease phenotypes have been attributed to abnormal synthesis, maintenance and composition of extracellular matrix (ECM), yet the molecular and cellular mechanisms causing these ECM defects remain po...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Melville, David B., Montero-Balaguer, Mercedes, Levic, Daniel S., Bradley, Kevin, Smith, Jeffrey R., Hatzopoulos, Antonis K., Knapik, Ela W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Limited 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209646/
https://ncbi.nlm.nih.gov/pubmed/21729877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007625
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