The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

Craniofacial and skeletal dysmorphologies account for the majority of birth defects. A number of the disease phenotypes have been attributed to abnormal synthesis, maintenance and composition of extracellular matrix (ECM), yet the molecular and cellular mechanisms causing these ECM defects remain po...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Melville, David B., Montero-Balaguer, Mercedes, Levic, Daniel S., Bradley, Kevin, Smith, Jeffrey R., Hatzopoulos, Antonis K., Knapik, Ela W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Limited 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209646/
https://ncbi.nlm.nih.gov/pubmed/21729877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.007625
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