The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes

Adeno-associated virus type 2 (AAV2) capsid assembly requires the expression of a virally encoded assembly-activating protein (AAP). By providing AAP together with the capsid protein VP3, capsids are formed that are composed of VP3 only. Electron cryomicroscopy analysis of assembled VP3-only capsids...

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Main Authors: Sonntag, F., Köther, K., Schmidt, K., Weghofer, M., Raupp, C., Nieto, K., Kuck, A., Gerlach, B., Böttcher, B., Müller, O. J., Lux, K., Hörer, M., Kleinschmidt, J. A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
主題:
Structure and Assembly
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209379/
https://ncbi.nlm.nih.gov/pubmed/21917944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05359-11
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