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Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
The Mre11 complex is a central component of the DNA damage response, with roles in damage sensing, molecular bridging, and end resection. We have previously shown that in Saccharomyces cerevisiae, Ku70 (yKu70) deficiency reduces the ionizing radiation sensitivity of mre11Δ mutants. In this study, we...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209331/ https://ncbi.nlm.nih.gov/pubmed/21876003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05854-11 |
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