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Replication of the Rotavirus Genome Requires an Active Ubiquitin-Proteasome System
Here we show that the ubiquitin-proteasome system is required for the efficient replication of rotavirus RRV in MA104 cells. The proteasome inhibitor MG132 decreased the yield of infectious virus under conditions where it severely reduces the synthesis of not only viral but also cellular proteins. A...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209302/ https://ncbi.nlm.nih.gov/pubmed/21900156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05286-11 |
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