Orthopoxviruses Require a Functional Ubiquitin-Proteasome System for Productive Replication

Cellular homeostasis depends on an intricate balance of protein expression and degradation. The ubiquitin-proteasome pathway plays a crucial role in specifically targeting proteins tagged with ubiquitin for destruction. This degradation can be effectively blocked by both chemically synthesized and n...

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Autores principales: Teale, Alastair, Campbell, Stephanie, Van Buuren, Nick, Magee, Wendy C., Watmough, Kelly, Couturier, Brianne, Shipclark, Robyn, Barry, Michele
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643736/
https://ncbi.nlm.nih.gov/pubmed/19109393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01753-08
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