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Replication of the Rotavirus Genome Requires an Active Ubiquitin-Proteasome System

Here we show that the ubiquitin-proteasome system is required for the efficient replication of rotavirus RRV in MA104 cells. The proteasome inhibitor MG132 decreased the yield of infectious virus under conditions where it severely reduces the synthesis of not only viral but also cellular proteins. A...

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Detaylı Bibliyografya
Asıl Yazarlar: López, Tomás, Silva-Ayala, Daniela, López, Susana, Arias, Carlos F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209302/
https://ncbi.nlm.nih.gov/pubmed/21900156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05286-11
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