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The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor β-Stimulated Aortic Endothelial Cells

Podosomes are dynamic actin-rich adhesion plasma membrane microdomains endowed with extracellular matrix-degrading activities. In aortic endothelial cells, podosomes are induced by transforming growth factor β (TGF-β), but how this occurs is largely unknown. It is thought that, in endothelial cells,...

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Main Authors: Daubon, Thomas, Buccione, Roberto, Génot, Elisabeth
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209245/
https://ncbi.nlm.nih.gov/pubmed/21911474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05474-11
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