ALK5 and ALK1 Play Antagonistic Roles in Transforming Growth Factor β-Induced Podosome Formation in Aortic Endothelial Cells

Transforming growth factor β (TGF-β) and related cytokines play a central role in the vascular system. In vitro, TGF-β induces aortic endothelial cells to assemble subcellular actin-rich structures specialized for matrix degradation called podosomes. To explore further this TGF-β-specific response a...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Curado, Filipa, Spuul, Pirjo, Egaña, Isabel, Rottiers, Patricia, Daubon, Thomas, Veillat, Véronique, Duhamel, Paul, Leclercq, Anne, Gontier, Etienne, Génot, Elisabeth
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248735/
https://ncbi.nlm.nih.gov/pubmed/25266657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01026-14
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