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Amplification Methods Bias Metagenomic Libraries of Uncultured Single-Stranded and Double-Stranded DNA Viruses

Investigation of viruses in the environment often requires the amplification of viral DNA before sequencing of viral metagenomes. In this study, two of the most widely used amplification methods, the linker amplified shotgun library (LASL) and multiple displacement amplification (MDA) methods, were...

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書目詳細資料
Main Authors: Kim, Kyoung-Ho, Bae, Jin-Woo
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209148/
https://ncbi.nlm.nih.gov/pubmed/21926223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00289-11
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