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Amplification Methods Bias Metagenomic Libraries of Uncultured Single-Stranded and Double-Stranded DNA Viruses

Investigation of viruses in the environment often requires the amplification of viral DNA before sequencing of viral metagenomes. In this study, two of the most widely used amplification methods, the linker amplified shotgun library (LASL) and multiple displacement amplification (MDA) methods, were...

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Detalhes bibliográficos
Main Authors: Kim, Kyoung-Ho, Bae, Jin-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209148/
https://ncbi.nlm.nih.gov/pubmed/21926223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00289-11
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