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Advantages of Single-Stranded DNA Over Double-Stranded DNA Library Preparation for Capturing Cell-free Tumor DNA in Plasma
PURPOSE: Single-stranded DNA (ssDNA) library has shown to enrich shorter and more degraded DNA fragments than double-stranded DNA (dsDNA) library. In this study, we evaluated whether ssDNA libraries capture more circulating tumor DNAs (ctDNAs) in plasma cell-free DNA (cfDNA). MATERIALS AND METHODS:...
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| Publicado no: | Mol Diagn Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7216418/ https://ncbi.nlm.nih.gov/pubmed/31654347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-019-00429-7 |
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