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Novel Recombinant Glycosylphosphatidylinositol (GPI)-Anchored ADAMTS13 and Variants for Assessment of Anti-ADAMTS13 Autoantibodies in Patients with Thrombotic Thrombocytopenic Purpura

Immunoglobulin Gs (IgGs) against ADAMTS13 are major causes of acquired (idiopathic) thrombotic thrombocytopenic purpura (TTP). We report here a novel cell-based assay using glycosylphosphatidylinositol (GPI)-anchored ADAMTS13 or variants expressed on cell membrane for assessment of autoantibodies in...

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Detalhes bibliográficos
Main Authors: Li, Dengju, Xiao, Juan, Paessler, Michele, Zheng, X. Long
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208768/
https://ncbi.nlm.nih.gov/pubmed/21901237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH11-05-0337
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