High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse

BACKGROUND: Resistance to therapy and subsequent relapse remain major challenges in the clinical management of relapsed childhood acute lymphoblastic leukemia. As the bone marrow environment plays an important role in survival and chemotherapy resistance of leukemia cells by activating different sig...

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Detalhes bibliográficos
Main Authors: Shalapour, Shabnam, Hof, Jana, Kirschner-Schwabe, Renate, Bastian, Lorenz, Eckert, Cornelia, Prada, Javier, Henze, Günter, von Stackelberg, Arend, Seeger, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208680/
https://ncbi.nlm.nih.gov/pubmed/21828124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.047993
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