High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse

BACKGROUND: Resistance to therapy and subsequent relapse remain major challenges in the clinical management of relapsed childhood acute lymphoblastic leukemia. As the bone marrow environment plays an important role in survival and chemotherapy resistance of leukemia cells by activating different sig...

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Hlavní autoři: Shalapour, Shabnam, Hof, Jana, Kirschner-Schwabe, Renate, Bastian, Lorenz, Eckert, Cornelia, Prada, Javier, Henze, Günter, von Stackelberg, Arend, Seeger, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208680/
https://ncbi.nlm.nih.gov/pubmed/21828124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.047993
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