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Antidepressants Stimulate Hippocampal Neurogenesis by Inhibiting p21 Expression in the Subgranular Zone of the Hipppocampus

The relationships among hippocampal neurogenesis, depression and the mechanism of action of antidepressant drugs have generated a considerable amount of controversy. The cyclin-dependent kinase (Cdk) inhibitor p21(Cip1) (p21) plays a crucial role in restraining cellular proliferation and maintaining...

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Bibliografiset tiedot
Päätekijät: Pechnick, Robert N., Zonis, Svetlana, Wawrowsky, Kolja, Cosgayon, Rosemarie, Farrokhi, Catherine, Lacayo, Liliana, Chesnokova, Vera
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208633/
https://ncbi.nlm.nih.gov/pubmed/22076148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027290
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