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p21(Cip1) restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus

The subgranular zone (SGZ) of the dentate gyrus of the hippocampus is a brain region where robust neurogenesis continues throughout adulthood. Cyclin-dependent kinases (CDKs) have a primary role in controlling cell division and cellular proliferation. p21(Cip1) (p21) is a CDK inhibitor that restrain...

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Detalhes bibliográficos
Main Authors: Pechnick, Robert N., Zonis, Svetlana, Wawrowsky, Kolja, Pourmorady, Jonathan, Chesnokova, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234143/
https://ncbi.nlm.nih.gov/pubmed/18172194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711030105
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