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Antidepressants Stimulate Hippocampal Neurogenesis by Inhibiting p21 Expression in the Subgranular Zone of the Hipppocampus

The relationships among hippocampal neurogenesis, depression and the mechanism of action of antidepressant drugs have generated a considerable amount of controversy. The cyclin-dependent kinase (Cdk) inhibitor p21(Cip1) (p21) plays a crucial role in restraining cellular proliferation and maintaining...

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Detaylı Bibliyografya
Asıl Yazarlar: Pechnick, Robert N., Zonis, Svetlana, Wawrowsky, Kolja, Cosgayon, Rosemarie, Farrokhi, Catherine, Lacayo, Liliana, Chesnokova, Vera
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208633/
https://ncbi.nlm.nih.gov/pubmed/22076148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027290
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