p53 Dependent Centrosome Clustering Prevents Multipolar Mitosis in Tetraploid Cells

BACKGROUND: p53 abnormality and aneuploidy often coexist in human tumors, and tetraploidy is considered as an intermediate between normal diploidy and aneuploidy. The purpose of this study was to investigate whether and how p53 influences the transformation from tetraploidy to aneuploidy. PRINCIPAL...

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Bibliografski detalji
Glavni autori: Yi, Qiyi, Zhao, Xiaoyu, Huang, Yun, Ma, Tieliang, Zhang, Yingyin, Hou, Heli, Cooke, Howard J., Yang, Da-Qing, Wu, Mian, Shi, Qinghua
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208627/
https://ncbi.nlm.nih.gov/pubmed/22076149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027304
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