p53 Dependent Centrosome Clustering Prevents Multipolar Mitosis in Tetraploid Cells

BACKGROUND: p53 abnormality and aneuploidy often coexist in human tumors, and tetraploidy is considered as an intermediate between normal diploidy and aneuploidy. The purpose of this study was to investigate whether and how p53 influences the transformation from tetraploidy to aneuploidy. PRINCIPAL...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yi, Qiyi, Zhao, Xiaoyu, Huang, Yun, Ma, Tieliang, Zhang, Yingyin, Hou, Heli, Cooke, Howard J., Yang, Da-Qing, Wu, Mian, Shi, Qinghua
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208627/
https://ncbi.nlm.nih.gov/pubmed/22076149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027304
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