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Acute Overactive Endocannabinoid Signaling Induces Glucose Intolerance, Hepatic Steatosis, and Novel Cannabinoid Receptor 1 Responsive Genes

Endocannabinoids regulate energy balance and lipid metabolism by stimulating the cannabinoid receptor type 1 (CB1). Genetic deletion and pharmacological antagonism have shown that CB1 signaling is necessary for the development of obesity and related metabolic disturbances. However, the sufficiency o...

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Main Authors: Ruby, Maxwell A., Nomura, Daniel K., Hudak, Carolyn S. S., Barber, Anne, Casida, John E., Krauss, Ronald M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208546/
https://ncbi.nlm.nih.gov/pubmed/22073164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026415
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