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Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins

The endocannabinoid (EC) system regulates food intake and energy metabolism. Cannabinoid receptor type 1 (CB1) antagonists show promise in the treatment of obesity and its metabolic consequences. Although the reduction in adiposity resulting from therapy with CB1 antagonists may not account fully fo...

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Detalhes bibliográficos
Main Authors: Ruby, Maxwell A., Nomura, Daniel K., Hudak, Carolyn S. S., Mangravite, Lara M., Chiu, Sally, Casida, John E., Krauss, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567196/
https://ncbi.nlm.nih.gov/pubmed/18794527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807232105
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