Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG

IDH1 SNP rs11554137 was recently reported in association with poor prognosis in normal karyotype adult acute myeloid leukemia (AML). We aimed to determine the prevalence, clinical associations, and prognostic significance of SNP rs11554137 in unselected pediatric and adult AML patients. Diagnostic m...

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Main Authors: Ho, Phoenix A., Kopecky, Kenneth J., Alonzo, Todd A., Gerbing, Robert B., Miller, Kristen L., Kuhn, Julia, Zeng, Rong, Ries, Rhonda E., Raimondi, Susana C., Hirsch, Betsy A., Oehler, Vivian, Hurwitz, Craig A., Franklin, Janet L., Gamis, Alan S., Petersdorf, Stephen H., Anderson, Jeanne E., Godwin, John E., Reaman, Gregory H., Willman, Cheryl L., Bernstein, Irwin D., Radich, Jerald P., Appelbaum, Frederick R., Stirewalt, Derek L., Meshinchi, Soheil
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2011
נושאים:
Clinical Trials and Observations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208275/
https://ncbi.nlm.nih.gov/pubmed/21873548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-348888
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