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Activation of OX40 Prolongs and Exacerbates Autoimmune Experimental Uveitis

PURPOSE. T cells are essential for the development of autoimmune uveitis. Although the costimulatory molecule OX40 promotes T-cell function and expansion, it is unclear whether OX40 is implicated in ocular inflammation. The purpose of this study was to examine the role of OX40 in uveitis. METHODS. E...

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書誌詳細
主要な著者: Wu, Xiumei, Rosenbaum, James T., Adamus, Grazyna, Zhang, Gary L., Duan, Jie, Weinberg, Andrew, Zhang, Zili
フォーマット: Artigo
言語:Inglês
出版事項: Association for Research in Vision and Ophthalmology, Inc. 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208192/
https://ncbi.nlm.nih.gov/pubmed/21948545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7664
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