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Low Dose Rapamycin Exacerbates Autoimmune Experimental Uveitis

BACKGROUND: Rapamycin, a potent immune modulator, is used to treat transplant rejection and some autoimmune diseases. Uveitis is a potentially severe inflammatory eye disease, and 2 clinical trials of treating uveitis with rapamycin are under way. Unexpectedly, recent research has demonstrated that...

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Detalhes bibliográficos
Main Authors: Zhang, Zili, Wu, Xiumei, Duan, Jie, Hinrichs, David, Wegmann, Keith, Zhang, Gary L., Hall, Mark, Rosenbaum, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344911/
https://ncbi.nlm.nih.gov/pubmed/22574188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036589
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