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Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells

The aim of this study was to evaluate the long-term effects of lithium treatment on neonatal hypoxic-ischemic brain injury, inflammation, and neural stem/progenitor cell (NSPC) proliferation and survival. Nine-day-old male rats were subjected to unilateral hypoxia-ischemia (HI) and 2 mmol/kg lithium...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Hongfu, Li, Qian, Du, Xiaonan, Sun, Yanyan, Wang, Xiaoyang, Kroemer, Guido, Blomgren, Klas, Zhu, Changlian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208156/
https://ncbi.nlm.nih.gov/pubmed/21587270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.75
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