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Activation of autophagy by alpha-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on STING
Autophagy has been established as a player in host defense against viruses. The mechanisms by which the host induces autophagy during infection are diverse. In the case of herpes simplex virus type 1 (HSV-1), dsRNA dependent protein kinase (PKR) is essential for induction of autophagy in fibroblasts...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208073/ https://ncbi.nlm.nih.gov/pubmed/21998456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100949 |
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