Interspecies Translation of Disease Networks Increases Robustness and Predictive Accuracy

Gene regulatory networks give important insights into the mechanisms underlying physiology and pathophysiology. The derivation of gene regulatory networks from high-throughput expression data via machine learning strategies is problematic as the reliability of these models is often compromised by li...

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Autors principals: Anvar, Seyed Yahya, Tucker, Allan, Vinciotti, Veronica, Venema, Andrea, van Ommen, Gert-Jan B., van der Maarel, Silvere M., Raz, Vered, ‘t Hoen, Peter A. C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207951/
https://ncbi.nlm.nih.gov/pubmed/22072955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002258
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