Interspecies Translation of Disease Networks Increases Robustness and Predictive Accuracy

Gene regulatory networks give important insights into the mechanisms underlying physiology and pathophysiology. The derivation of gene regulatory networks from high-throughput expression data via machine learning strategies is problematic as the reliability of these models is often compromised by li...

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Détails bibliographiques
Auteurs principaux: Anvar, Seyed Yahya, Tucker, Allan, Vinciotti, Veronica, Venema, Andrea, van Ommen, Gert-Jan B., van der Maarel, Silvere M., Raz, Vered, ‘t Hoen, Peter A. C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207951/
https://ncbi.nlm.nih.gov/pubmed/22072955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002258
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