Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

The choice for a polyadenylation site determines the length of the 3′-untranslated region (3′-UTRs) of an mRNA. Inclusion or exclusion of regulatory sequences in the 3′-UTR may ultimately affect gene expression levels. Poly(A) binding protein nuclear 1 (PABPN1) is involved in polyadenylation of pre-...

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Autores principales: de Klerk, Eleonora, Venema, Andrea, Anvar, S. Yahya, Goeman, Jelle J., Hu, OuHua, Trollet, Capucine, Dickson, George, den Dunnen, Johan T., van der Maarel, Silvère M., Raz, Vered, ‘t Hoen, Peter A. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467053/
https://ncbi.nlm.nih.gov/pubmed/22772983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks655
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