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Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control
BACKGROUND: The effects and effectiveness of the chaperone pair GroELS on the yield and quality of recombinant polypeptides produced in Escherichia coli are matter of controversy, as the reported activities of this complex are not always consistent and eventually indicate undesired side effects. The...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207889/ https://ncbi.nlm.nih.gov/pubmed/21992454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-79 |
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