Intestinal deletion of Pofut1 in the mouse inactivates Notch signaling and causes entero-colitis

BACKGROUND & AIMS: Notch downstream targets are fundamental to intestinal cell lineage commitment and are suggested as therapeutic targets for colon cancer cells. However, the role of endogenous Notch signaling through receptor-ligand interaction, and effects of its longer-term down-regulation o...

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Detaylı Bibliyografya
Asıl Yazarlar: Guilmeau, Sandra, Flandez, Marta, Bancroft, Laura, Sellers, Rani S., Tear, Benjamin, Stanley, Pamela, Augenlicht, Leonard H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207497/
https://ncbi.nlm.nih.gov/pubmed/18621050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.05.050
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