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Crystal Structure of C-terminal Truncated Apolipoprotein A-I Reveals the Assembly of High Density Lipoprotein (HDL) by Dimerization

Apolipoprotein A-I (apoA-I) plays important structural and functional roles in plasma high density lipoprotein (HDL) that is responsible for reverse cholesterol transport. However, a molecular understanding of HDL assembly and function remains enigmatic. The 2.2-Å crystal structure of Δ(185–243)apoA...

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Détails bibliographiques
Auteurs principaux: Mei, Xiaohu, Atkinson, David
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207425/
https://ncbi.nlm.nih.gov/pubmed/21914797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260422
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