The antiviral protein viperin inhibits HCV replication via interaction with NS5A

The interferon-stimulated gene viperin has been shown to have antiviral activity against hepatitis C virus (HCV) in the context of the HCV replicon, although the molecular mechanisms responsible are not well understood. Here we demonstrate that viperin plays an integral part in the ability of interf...

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Bibliografiske detaljer
Main Authors: Helbig, Karla J., Eyre, Nicholas S., Yip, Evelyn, Narayana, Sumudu, Li, Kui, Fiches, Guillaume, McCartney, Erin M., Jangra, Rohit K., Lemon, Stanley M., Beard, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207276/
https://ncbi.nlm.nih.gov/pubmed/22045669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24542
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