Hepatitis C Virus (HCV) NS3 Sequence Diversity and Antiviral Resistance-Associated Variant Frequency in HCV/HIV Coinfection

HIV coinfection accelerates disease progression in chronic hepatitis C and reduces sustained antiviral responses (SVR) to interferon-based therapy. New direct-acting antivirals (DAAs) promise higher SVR rates, but the selection of preexisting resistance-associated variants (RAVs) may lead to virolog...

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Hlavní autoři: Jabara, Cassandra B., Hu, Fengyu, Mollan, Katie R., Williford, Sara E., Menezes, Prema, Yang, Yan, Eron, Joseph J., Fried, Michael W., Hudgens, Michael G., Jones, Corbin D., Swanstrom, Ronald, Lemon, Stanley M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187920/
https://ncbi.nlm.nih.gov/pubmed/25092699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03466-14
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