Viperin Is Induced following Dengue Virus Type-2 (DENV-2) Infection and Has Anti-viral Actions Requiring the C-terminal End of Viperin

The host protein viperin is an interferon stimulated gene (ISG) that is up-regulated during a number of viral infections. In this study we have shown that dengue virus type-2 (DENV-2) infection significantly induced viperin, co-incident with production of viral RNA and via a mechanism requiring reti...

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Autori principali: Helbig, Karla J., Carr, Jillian M., Calvert, Julie K., Wati, Satiya, Clarke, Jennifer N., Eyre, Nicholas S., Narayana, Sumudu K., Fiches, Guillaume N., McCartney, Erin M., Beard, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630087/
https://ncbi.nlm.nih.gov/pubmed/23638199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002178
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